Dermal Models

MLM Medical Labs specializes in dermal research with a host of validated preclinical models and translational services supported by a range of read-outs including protein and mRNA analyses, histology and flow cytometry.

Validated models include:

  • Imiquimod (IMQ) induced Psoriasis Model

  • IL-23-induced Psoriasis Model
  • Fluorescein Isothiocyanate (FITC) and Dinitrochlorobenzene (DNCB) Contact Dermatitis
  • Oxazolone-induced Delayed Type Hypersensitivity (DTH) Model
  • Passive Cutaneous Anaphylaxis Model
  • MC903-induced Atopic Dermatitis

Available readouts:

  • Clinical score
  • Ear thickness
  • Biomarker analysis (mRNA or protein)
  • Cell populations in spleen/lymph nodes by flow cytometry
  • Histology/IHC
  • PK blood collections
Preclinical Dermal Models
View datasheets in Our Knowledge Library

Are you interested in a variation of a model or a new paradigm?

Our scientists are passionate about the development of new models! We often participate in opportunities for co-development and pilot programs to establish new models and reach new levels of understanding.