Arthritis Models

Models of immune-mediated arthritis (RMIA) are commonly used to evaluate the mechanisms of inflammatory joint disease, as well as test the efficacy of anti-arthritic compounds.

Our expertise includes:

  • Adjuvant-induced Rheumatoid Arthritis (AIA)
  • Collagen antibody-induced Rheumatoid Arthritis (CAIA)
  • Collagen-induced Rheumatoid Arthritis (CIA)

Available readouts options:

  • Circulating or tissue level biomarker analysis (protein or mRNA)
  • Collagen antibody levels
  • Cell populations in spleen/lymph node by flow cytometry
  • Histological/IHC assessment of joints
  • PK blood collections
arthritis-models
View datasheet in Our Knowledge Library

Are you interested in a variation of a model or a new paradigm?

Our scientists are passionate about the development of new models! We often participate in opportunities for co-development and pilot programs to establish new models and reach new levels of understanding.

Questions? Speak with our expert

Reach out to our Director of Business Development, Preclinical
to discuss your custom needs. 

-> E-Mail Katie Dineen, B.S

-> Download Preclinial Brochure