Sepsis Models The pathology of Sepsis in humans is poorly understood. Sepsis is a common syndrome that is responsible for killing thousands of patients worldwide each year and is primarily described as inflammation in the setting of infection. At MLM Medical Labs, we use the bacteria lipopolysaccharide (LPS) to induce sepsis, which triggers  an immune […]

Inflammatory Bowel Disease Models Human Inflammatory Bowel Disease (IBD) encompassing two main illnesses, Crohn’s disease and Ulcerative Colitis, are chronic wasting conditions of unknown etiology for which there is still no known cure. They are characterized clinically by diarrhea and body weight loss. For this reason, at MLM, we offer the trinitrobenzene sulfonic acid (TNBS)

Metabolic Models Obesity presents an enormous burden on health and its negative side effects extend across multiple organ systems and diseases. It is a major risk factor for cardiovascular disease, diabetes, stroke, certain cancers, osteoarthritis, gastrointestinal, reproductive disorders and pulmonary diseases. Additionally, obesity triggers a low grade inflammatory response which involves many components of a

Dermal Models MLM Medical Labs specializes in dermal research with a host of validated preclinical models and translational services supported by a range of read-outs including protein and mRNA analyses, histology and flow cytometry. Validated models include: Imiquimod (IMQ) induced Psoriasis Model IL-23-induced Psoriasis Model Fluorescein Isothiocyanate (FITC) and Dinitrochlorobenzene (DNCB) Contact Dermatitis Oxazolone-induced Delayed

Respiratory Models Lung Inflammation is a critical component of many lung diseases including Asthma. Asthma is classified as a chronic inflammatory disease of the airways, however the underlying physiology and immunological pathways are not completely understood. Allergen challenge models are commonly used to study mechanisms involved in lung inflammation and allergic Asthma. MLM Medical Labs

Arthritis Models Models of immune-mediated arthritis (RMIA) are commonly used to evaluate the mechanisms of inflammatory joint disease, as well as test the efficacy of anti-arthritic compounds. Our expertise includes: Adjuvant-induced Rheumatoid Arthritis (AIA) Collagen antibody-induced Rheumatoid Arthritis (CAIA) Collagen-induced Rheumatoid Arthritis (CIA) Available readouts options: Circulating or tissue level biomarker analysis (protein or mRNA)

Biological Sample Management Your Samples Are in Good Hands – Globally! Your biological samples are invaluable. That is why we developed the MLM Sample Storage System® to guarantee the traceability and integrity of your samples at all times. Our European and North American storage facilities provide short- and long-term cryopreservation and biostorage solutions for over

MLM Safeguard Box® and Packaging Clever logistics solution to bring you peace of mind​ Rapid temperature changes significantly impact the results of sample analyses. Our smart packaging system, the MLM Safeguard Box®, protects against thermal stress and stabilizes your samples efficiently during transport. This clinical logistics innovation was created with our customers and clinical sites

MLM Kit Building® Customized Clinical Trial Kit Building With Full Flexibility​ Reliable sample management directly impacts protocol adherence, data quality and trial timelines. MLM Kit Building® provides customized clinical sample kit services from MLM Medical Labs to simplify and optimize the sample management process. Our advanced solutions facilitate seamless collection, storage and shipment of valuable clinical

Global Logistics Improving Patient Outcomes, One Sample at a Time At MLM Medical Labs we pride ourselves on our analytical and scientific quality, for which sample integrity is of the utmost importance. To achieve that we combine thorough courier selection and management as well as clever packaging solutions. Based on the sample types, stability needed