Infectious Disease Trials,
Accelerated in Africa.
A Strategic Advantage for HIV, TB, and Malaria Clinical Trials in Africa
HIV, tuberculosis (TB), and malaria continue to represent three of the world’s most critical infectious disease challenges—driving urgent innovation in both vaccine and therapeutic development. Africa remains the epicenter of this research, with the largest treatment-naïve patient populations, diverse genomic representation, and robust investigator networks.
MLM Medical Labs and Cytespace Africa Laboratories bring unmatched scientific and operational strength to HIV, TB, and Malaria clinical trials—accelerating site activation, enrollment, and data delivery without compromise.
Accelerating HIV, TB, and Malaria Trials—From Pretoria to the World
Whether developing next-generation vaccines or evaluating therapeutic interventions, sponsors face complex demands: fast enrollment, data integrity, regulatory alignment, and reliable logistics across multiple regions.
That’s exactly where MLM Medical Labs and Cytespace Africa Laboratories thrive.
With a fully CAP-accredited facility in Pretoria, embedded logistics across Sub-Saharan Africa, and harmonized SOPs within MLM’s global network, we enable sponsors to launch and manage HIV, TB, and malaria studies seamlessly—supported by centralized data integration and end-to-end oversight.
Core Benefits of Our African Central Lab Platform:
■ Faster startup timelines through in-region kit production, site support, and regulatory familiarity
■ Diverse access to HIV, TB, and malaria patient populations across Sub-Saharan Africa
■ Full-service testing capabilities for vaccine and therapeutic trials
■ Single-source lab partnership integrated with MLM’s operations in Europe and North America
■ Full-service, end-to-end support from first sample to final database lock
■ Overnight sample delivery within South Africa for reduced TATs
■ Single global database through MLM’s global informatics platform
Our Cytespace Africa Laboratories facility doesn’t operate in isolation. It’s fully integrated with MLM’s global quality systems, scientific teams, and data management workflows—so you get the operational efficiency of a local lab with the oversight and audit readiness of a global one.
Whether you’re running a vaccine trial, therapeutic protocol, or regional epidemiology study, this integration means you don’t have to choose between speed and standards. You get both.
Vaccine Development Trials: Immunogenicity and Efficacy at Scale
Africa’s infectious disease vaccine trials demand precision in immune monitoring, assay validation, and biospecimen management.
Cytespace Africa Laboratories Provides:
■ PBMC isolation, cryopreservation, and recovery services for immunogenicity testing
■ Flow cytometry for CD4/CD8 immune profiling
■ ELISPOT and cytokine release assays for vaccine response evaluation
■ Cold-chain management for sample integrity across study sites
■ Integration with MLM’s global database management systems for 24/7 access to trial data
Therapeutic Development Trials: Targeted, Validated, and Accelerated
For therapeutic development in infectious diseases, rapid diagnostics, biomarker validation, and accurate endpoints are critical.
Our TB/HIV/Malaria therapeutic support includes:
■ TB: Comprehensive diagnostic suite—microscopy, culture (LJ + liquid), DST, MIC, and QuantiFERON® TB Gold Plus
■ HIV: Serological and molecular diagnostic assays, viral load quantification, and CD4/CD8 monitoring
■ Malaria: PCR-based detection and quantification, microscopy, and antigen-based rapid diagnostic validation
■ Custom assay development to meet protocol-specific endpoints
■ High-throughput platforms for large-scale studies and adaptive trial designs
Specialized Infrastructure and Expertise
■ Two Biosafety Level 3 (BSL-3) laboratories for complex TB and HIV research
■ Validated molecular and immunological platforms for all three core diseases continuity
■ Locally led, scientifically trained teams with 30+ years of regional experience
■ Integration with MLM’s global network for a single source of data and oversight
Operational Readiness from Site Initiation
■ Tailored kit building to ensure accuracy and consistency across sites
■ Validated cold-chain logistics across Sub-Saharan Africa
■ 24/7 electronic monitoring, redundant power, and chain-of-custody traceability
■ Overnight delivery within South Africa and rapid cross-border clearance
Biobanking and Long-Term Study Support
■ Ultra-low temperature biobanking (−70°C to −86°C) powered by solar energy
■ Ideal for longitudinal vaccine and therapeutic studies requiring extended sample retention
■ Integrated with MLM’s global data systems for unified audit-ready oversight
Experience at Scale
■ Over 1,250 clinical trials completed
■ 950,000+ patients supported
■ GCP- and GCLP-certified teams with deep HIV, TB, and malaria expertise
■ 98% employee retention ensuring consistency and continuity across long-term studies
Every result we generate is backed by a quality system designed for global oversight. Our lab is certified and accredited to the highest international standards, and we’ve built digital systems, audit pathways, and SOP frameworks to ensure data integrity across every stage of the trial lifecycle.
Quality Credentials:
■ Fully CAP-accredited — the only such central lab in South Africa
■ ISO 15189 certified
■ Fully aligned with ICH GCP, WHO GCLP, and sponsor audit standards
■ Digitally managed SOPs, CAPAs, QC systems, and document control (CEREBRO)
Talk to Our Infectious Disease Lab Experts
Let’s talk strategy, timelines, and how MLM + Cytespace Africa Laboratories can deliver what your study demands—start to finish. CONTACT US to get the conversation started.
