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  • Assay Development and Validation
  • PBMC Processing
  • Flow Cytometry
  • Biomarkers in Alzheimer’s Detection
  • Cell & Gene Therapy
  • Animal Nutrition
  • Medical Device Support

GLOBAL ACCESS TO HIGH-QUALITY PBMCs

A global network of highly-trained staff to isolate PBMCs per client-specific protocols and SOPs

In the rapidly evolving landscape of biopharma drug development, the need for precise, reliable, and scalable cellular resources has never been more critical. At MLM Medical Labs, we specialize in providing high-quality Peripheral Blood Mononuclear Cells (PBMCs) to support cutting-edge research and development across a variety of therapeutic areas. Through our highly qualified network of PBMC laboratories, we offer global access to PBMC isolations, ensuring consistency and reliability across different regions to meet the complex demands of international clinical trials and drug development initiatives.

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Same day PBMC Isolations
Download our PBMC Capabilities sheet
PBMC Isolation Services
  • PBMC isolation, liquid nitrogen biobanking
  • Same-day processing (goal = 5 hours from receipt)
  • Customized SOPs to meet your study-specific requirements
  • DNA/RNA extraction and assessment of quantity, quality, and purity of specific cell subsets
  • Cryopreserved PBMC Viability Testing
  • Immunophenotyping and Functional Assays
  • PBMC-based Assay Development and Validation for PK/PD Studies
Sample Collection Tubes Used
  • Whole Blood Tubes
  • EDTA
  • LiHep
  • CPT System Tubes
  • ctDNA/cfDNA Streck Tubes
  • Sodium Citrate
  • ACD-A
  • PAXgene Tubes

PBMC Data Quality

Viability

> 95%

Post Thaw Viability

> 80%

PBMC Biobanking and Comprehensive Analytical Assays

Regarding downstream analysis of isolated PBMCs, MLM provides liquid nitrogen biobanking, cryopreservation and offers a broad portfolio of analytical techniques, ranging from harmonized flow cytometry, genetic analyses to ELISA-based assays.

Wide Range of Storage Options
  • Short-term or long-term (more than 20 years) storage
  • Ambient, -20/30°C, -70/80°C and liquid nitrogen
  • Scalable storage capacities in Europe and North America
  • Harmonized 21CFR Part 11 compliant biospecimen management system
Specialized Expertise and Localized Support
  • All MLM Labs and PBMC Network labs are staffed with highly-trained local experts and technical support teams who understand regional regulations, logistical challenges, and specific client needs.
  • All lab personnel undergo comprehensive training to ensure seamless integration of PBMC isolation services into global clinical workflows.
Speak with our Experts ➔
The MLM Global PBMC Network

In addition to our state-of the-art PBMC processing labs in the U.S. and Germany, MLM has developed a carefully selected and meticulously screened network of partner labs across 5 continents to ensure rapid isolation turnaround times to meet your study demands

Consistency and Reliability Across Borders
  • Our collection and processing operating procedures are customized across all laboratory sites to meet the client’s SOPs. Strict adherence to the study’s SOPs and rigorous quality control ensures uniformity in PBMC isolation and handling, regardless of where the samples are collected.
  • MLM Medical Labs is GCLP-compliant and maintains CLIA, CAP, and ISO accreditations and certifications, along with strict adherence to global regulatory standards, providing confidence to sponsors that their samples are processed consistently worldwide.
Scalable Solutions for Global Clinical Trials:
  • MLM’s Global Logistics Department, in coordination with our Global PBMC Network, can manage high volumes of samples across different regions, based on extensive experience managing PBMC processing for global, multi-center clinical trials.
  • MLM is highly regarded for operational flexibility and scalability and supports complex projects from early-phase trials to late-stage studies.
Customized Shipping and Handling Solutions

The MLM Global Logistics department designs tailored shipping solutions for each study that prioritize sample integrity, leveraging state-of-the-art cold chain logistics and temperature-controlled packaging to minimize sample degradation during transit.

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