In a recent paper from the group of Prof. Lammert, University of Dusseldorf, Germany, in Nature Medicine (Marquardt et al., Nature Medicine 21 (2015) 363–372) extensive investigations on the effect of the NMDA-receptor antagonist dextromethorphan on pancreatic
Nature Medicine: NMDA-Receptor antagonist affects pancreatic islet cells Read More »
The draft guideline published by the FDA defines the criteria that have to be fulfilled by analytical methods used for the assessment of drug compounds and their metabolites and of biomarkers.
FDA issued draft guidance on Bioanalytical Method Validation Read More »
MLM has been founded 20 years ago on September 9, 1993. For the first fifteen years we have supported clinical studies with the infrastructure of a clinical reference laboratory. Within the last five years
MLM celebrates 20 years anniversary Read More »
For new drug candidates that are potentially affecting the renal function the assessment of the glomerular filtration rate (GFR) and the effective renal plasma flow (ERPF) may be helpful to test nephrotoxicity.
Robust method for iohexol and para-aminohippuric acid analysis in plasma Read More »
